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Iron Topics
Iron metabolism is shaped by iron's status as an essential nutrient for which there is no mechanism for excreting any excesses that may accumulate in the body.

Iron absorption is affected by the form in which iron is presented to the digestive tract, and inorganic iron ions change oxidation state during the absorption process.

Regulation of iron uptake occurs at the basal membrane of the intestinal mucosal cells. These cells make an iron-binding protein, apoferritin.

Iron transport and storage involve changes of oxidation state. The capacity of the plasma to transport iron is of clinical interest. Excess stored iron can cause pathology.

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