A patient with blockage of hepatic biliary network:

A. Increased "Indirect" bilirubin in blood
B. Increased "Direct" bilirubin in blood
  1. A only
  2. B only
  3. Both A and B
  4. Neither A or B


In this situation bilirubin becomes conjugated, but secretion of the conjugated (direct) bilirubin is blocked, so it accumulates in the blood. Conjugated bilirubin is referred to as direct bilirubin because, due to its water solubility, it reacts directly
in the van den Bergh test for bilirubin.

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